Design and Synthesis of (E)-4-(2-Phenyl-2H-chromen-3-yl)but-3-en-2-ones and Evaluation of their In Vitro Antimicrobial Activity
Letters in Organic Chemistry, 2015, 12, 1-7 Design and Synthesis of ( E )-4-(2-Phenyl-2 H -chromen-3-yl)but-3-en-2-ones and Evaluation of their In Vitro Antimicrobial Activity Sabita Nayak 1,* , Subhendu Chakroborty 1 , Sujitlal Bhakta 1 , Pravati Panda 1 , Seetaram Mohapatra 1 , Sanjeet Kumar 2 , Padan Kumar Jena 2 and Chandrasekhar Purohit 3 1 Department of Chemistry and 2 Department of Botany, Ravenshaw University, Cuttack, Odisha, India; 3 National Insti- tute of Science Education and Research, Bhubaneswar, Odisha, India Received January 23, 2015: Revised March 10, 2015: Accepted March 25, 2015 Abstract: 2 H -Chromene and its derivatives are an important class of organic compounds due to their wide range of bio- logical activities such as antimicrobial, antiviral, antiimflamatory and antitubercular agents. In the present work we have synthesized ten ne